Current epidemiological aspects of acute viral hepatitis in Russia

The purpose. Determine the current trends of the epidemic process of acute viral hepatitis (AVH): in the conditions of polyethylene friendliness, the influence of socio-economic changes taking place in the Russian Federation and measures of specific immunoprophylaxis of hepatitis B and A. Methods. The analysis of the data of the state statistical reporting of acute viral hepatitis in the Russian Federation (Form No. 2 "Information on infectious and parasitic diseases") was carried out, the analytical tables developed by the Pasteur Research Institute of Epidemiology and Microbiology and the Reference Center for Monitoring Viral Hepatitis of the FBSI Central were analyzed. Research Institute of Epidemiology of Rospotrebnadzor. To establish the occurrence of polyetiology, a serological study was carried out by ELISA of 275 blood samples obtained from patients hospitalized in an infectious diseases hospital with a laboratory-confirmed diagnosis of hepatitis A (HAVAb IgM) for the presence of HBV markers: HBsAg, HBsAb, HBcAb and HCV: HCVAb. Results. The incidence of acute viral hepatitis has reached the elimination rate in children and adults. In 2009 the incidence of acute hepatitis C was 2.2 per 100 thousand of the population, in children under 14 years old - 0.6 per 100 thousand of the population, and in 2020 the rate decreased to 0.66 per 100 thousand of the population in the whole country up to 0.1 in children. A characteristic feature of the modern epidemic process of GA is the shift in incidence to age groups (20-39 years). The most common variants of polyetiology are HAV+ HBV (74%) Conclusion. The current trend in the epidemiology of AVH is a steady decrease in the incidence. The number of new cases of registration of both vaccine-controlled and non-managed AVH has been steadily declining in both children and adults. The most common variants of polyetiology are HAV+ HBV (74%).Vaccinal prophylaxis of HAV and HBV remains a necessary measure to combat various variants of the course of mixed infections.