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= 32). The patients were assessed for incidence and severity of nausea and vomiting at intervals of 0-1, 1-6, and 6-24 hours after extubation. Results: The incidence of nausea was as follows among patients: 72 (20.8%) in the ondansetron group, 23.6% in the dexamethasone group, 25.0% in the metoclopramide group, and 30.5% in the control group. Vomiting was found in 49 patients with an incidence rate of 8.1%, 16.3%, 36.7% and 38.7%, in ondansetron, dexamethasone and metoclopramid groups, respectively. The highest incidence of the initial nausea symptom occurred at the 1-6 hour interval in all groups (P = 0.034). Only ondansetron (P = 0.005) and dexamethasone (P = 0.019) were effective in preventing nausea at the 0-1 hour interval. The severity of nausea in patients who received dexamethasone was less. Conclusions: Ondansetron was more effective than dexamethasone and metoclopramide in preventing vomiting after laparoscopic cholecystectomy at intervals of 0-1 and 1-6 hours. Ondansetron delayed the interval of the first onset of nausea and vomiting.

women's health bulletin

Comparative Study of the Effectiveness of Ondansetron, Metoclopramide and Low Dose Dexamethasone to Prevent Postoperative Nausea and Vomiting in Females who Undergo Laparoscopic Cholecystectomy