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Cytotoxic Effects of the Ethanol Bane Skin Extract in Human Prostate Cancer Pc3 Cells
Author(s) -
Maryam Amiri,
Faranak Kazerouni,
Saeed Namaki,
Hassan Darbandi Tamijani,
Hooman Rahimipour,
Nasrin Boroumand,
Siyamak Barghi,
Nazanin Ebrahimi,
Seyed Mohammad Gheibi Hayat
Publication year - 2016
Publication title -
iranian journal of cancer prevention
Language(s) - English
Resource type - Journals
eISSN - 2008-2401
pISSN - 2008-2398
DOI - 10.17795/ijcp-4755
Subject(s) - cytotoxic t cell , medicine , apoptosis , cancer cell , pharmacology , ic50 , cell culture , ethanol , mtt assay , cytotoxicity , human skin , cancer , in vitro , biochemistry , chemistry , biology , genetics
The ethanol Bane skin extract could repress the growth of PC3 cell line. This inhibitory effect of the Bane extract depended on the dose and the time on PC3. The result of this study shows that the ethanol Bane skin extract includes photochemical and inhibitory function against proliferation and inducer of apoptosis in human prostate cancer PC3 cells and also has less cytotoxic effect on l929 than PC3 cells. The ethanol Bane skin extract might be a good candidate for the new herbal anticancer drug.

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