Nanocarriers Usage for Drug Delivery in Cancer Therapy
Author(s) -
Hadi Khodabandehloo,
Hamid Zahednasab,
Asghar Ashrafi Hafez
Publication year - 2016
Publication title -
iranian journal of cancer prevention
Language(s) - English
Resource type - Journals
eISSN - 2008-2401
pISSN - 2008-2398
DOI - 10.17795/ijcp-3966
Subject(s) - nanocarriers , medicine , drug carrier , liposome , drug delivery , site of action , drug , dendrimer , cancer therapy , pharmacology , targeted drug delivery , therapeutic index , nanomedicine , nanotechnology , cancer , materials science , nanoparticle , polymer chemistry
Conventional therapeutic agents have displayed significant shortcomings. For this reason, important achievements have effectively made in biotechnology for delivering the therapeutic agents to the site of action, and diminish side effects. Polymeric carriers, micelles, dendrimers, liposomes, solid lipid carriers, gold carriers, viral carriers, nanotubes and magnetic carriers incorporating cytotoxic therapeutics have developed. To improve biological distribution of therapeutic drugs, some modified carriers have designed in optimal size and modified surface area. Delivery of carriers to target cells could be done by passive and active targeting.
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