Polymorphous Low-Grade Adenocarcinoma of the Palate: A Rare Case Report
Author(s) -
Sathyanarayanan Ramanujam,
Venkatachalam Suresh,
Beena Agnes Therese Thomas
Publication year - 2015
Publication title -
iranian journal of cancer prevention
Language(s) - English
Resource type - Journals
eISSN - 2008-2401
pISSN - 2008-2398
DOI - 10.17795/ijcp-3447
Subject(s) - medicine , lesion , adenocarcinoma , tongue , hard palate , biopsy , metastasis , differential diagnosis , papillary adenocarcinoma , pathology , surgery , cancer
The site of predilection of PLGA is more in favor of palate (49 - 77.8%) followed by either upper lip or buccal mucosa (7.4 - 13.4%). There are sporadic reports of metastasis sometimes even transformation to a high grade adenocarcinoma, sometimes ending in mortality. Cervical lymph node metastasis is rare with reported incidence of 5 - 15% and is more commonly seen in recurrent tumor than the initial diseases. Extra palatal PLGAs present with significant papillary growth or arising from ventral surface of tongue frequently metastasize to cervical lymph nodes. Distant metastasis is very rare with an incidence of 7.5% and the site involved is the lung which is attributed to the inadequate control of the disease.
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