Protective Effect of Vitamin E Against Lead-induced Memory and Learning Impairment in Male Rats
Author(s) -
Iraj Salehi,
Maryam Soleimani,
Mahsa Poorhamze,
Fahimeh Ghasemi Moravej,
Alireza Komaki,
Sara Soleimani Asl
Publication year - 2015
Publication title -
avicenna journal of neuro psych physiology
Language(s) - English
Resource type - Journals
eISSN - 2383-2444
pISSN - 2383-2436
DOI - 10.17795/ajnpp-27267
Subject(s) - memory impairment , vitamin , lead exposure , psychology , medicine , audiology , developmental psychology , neuroscience , cognition , cats
Results: The results showed that Pb caused impairment in acquisition and retrieval processes in passive avoidance learning. Vitamin E reversed learning and memory deficits in pre, post or co- exposure with Pb (P < 0.001). Conclusions: According to the results of this study, administration of vitamin E to rats counteracts the negative effects of Pb on learning and memory. To more precisely extrapolate these findings to humans, future clinical studies are warranted.
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