Effect of Lemon Verbena on Memory of Male Rats

Results: Analysis of data showed that in comparison to controls, treatment with the aqueous extract of lemon verbena (≥ 100 mg/kg) had decreased the step-through latency (STL) (P < 0.001). Moreover, treatment of the rats with the extract doses of ≥ 500 mg/kg had increased the total time spent in the dark compartment (TDC) in comparison to controls (P < 0.001). Conclusions: These results indicated that aqueous extract of lemon verbena (≥ 100 mg/kg) has undesirable effects on memory; however, understanding the underling mechanisms needs further investigation.