Antibacterial Effects of Origanum vulgare Essence Against Multidrug-Resistant Acinetobacter baumannii Isolated From Selected Hospitals of Tehran, Iran | Zendy

Hossein Saghi | Zendy; Abbas Bahador | Zendy; Azad Khaledi | Zendy; Ramazanali Ataee Kachoei | Zendy; Ferdoes Amiri Dastjerdi | Zendy; Davoud Esmaeili | Zendy

Open Access

Antibacterial Effects of Origanum vulgare Essence Against Multidrug-Resistant Acinetobacter baumannii Isolated From Selected Hospitals of Tehran, Iran

Author(s) -

Hossein Saghi,

Abbas Bahador,

Azad Khaledi,

Ramazanali Ataee Kachoei,

Ferdoes Amiri Dastjerdi,

Davoud Esmaeili

Publication year - 2015

Publication title -

avicenna journal of clinical microbiology and infection

Language(s) - English

Resource type - Journals

eISSN - 2383-0301

pISSN - 2383-0298

DOI - 10.17795/ajcmi-22982

Subject(s) - acinetobacter baumannii , origanum , antimicrobial , pulegone , multiple drug resistance , essential oil , carvacrol , menthone , pseudomonas aeruginosa , minimum inhibitory concentration , microbiology and biotechnology , traditional medicine , biology , medicine , bacteria , food science , drug resistance , genetics

Results: Analysis of the essential oil revealed the presence of pulegone (68.59%) piperitone (7.8%), piperitenone (7.8%), 1, 8-cineole (1.3%), and carvacrol (1.6%) as the major components. The results showed a significant activity against MDR A. baumannii with inhibition zones and minimal inhibitory concentration values in the ranges of 7-15 mm and 20-35 µL/mL respectively. Conclusions: This investigation showed that the essence oil of O. vulgare had a potent antimicrobial activity against MDR A. baumannii. Further research is required to evaluate the practical values of therapeutic applications.

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