Production Cross–Section Calculations of Medical 177Lu Using Neutron and Proton Induced Reactions

. In this study, we aimed to investigate the alternative ways to produce 177 Lu, an isotope which has a growing rate of usage in radionuclide therapy applications. For this purpose; we analyzed the 176 Lu (n,γ) 177 Lu, 176 Yb (n,γ) 177 Yb 177 Lu, 181 Ta (n,n+α) 177-M Lu, nat W(p,x) 177 Lu reactions with the TALYS 1.6 and EMPIRE 3.2 theoretical nuclear reaction codes. Obtained results with the TALYS 1.6 and EMPIRE 3.2 codes are also compared with the experimental data exists in the literature for each reaction. Keywords: 177 Lu, Cross–Section, TALYS 1.6, EMPIRE 3.2. Ozet. Bu calismada, radyonuklit terapi uygulamalarinda giderek artan bir kullanim oranina sahip olan 177 Lu izotopu icin alternatif uretim yollarinin arastirilmasi amaclanmistir. Bu amacla; 176 Lu(n,γ) 177 Lu, 176 Yb(n,γ) 177 Yb 177 Lu, 181 Ta(n,n+α) 177-M Lu, nat W(p,x) 177 Lu reaksiyonlari TALYS 1.6 ve EMPIRE 3.2 teorik nukleer reaksiyon kodlari kullanilarak analiz edilmistir. Ayrica, TALYS 1.6 ve EMPIRE 3.2 kodlari ile elde edilen bulgular her bir reaksiyon icin literaturde mevcut deneysel veriler ile karsilastirilmistir. Anahtar Kelimeler: 177 Lu, Tesir Kesiti, TALYS 1.6, EMPIRE 3.2.