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Published by United Scientific Group We are grateful to authors of the commentary "POLG1/ANT1-Related SANDO is a Multisystem Mitochondrial Disorder", which highlights our previous paper “Distinctive cerebral neuropathology in an adult case of sensory ataxic neuropathy with dysarthria and ophthalmoplegia (SANDO) syndrome" [1]. Josef Finsterer's and Sinda Zarrouk-Mahjoub's comments about the wellknown multi-system character in general, and cardiac complications in particular, of mitochondriopathies including SANDO are well taken, while we are not sure why the authors have concerns.

Response to Commentary “POLG1/ANT1-Related SANDO is a Multisystem Mitochondrial Disorder”