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Psychomotor agitation is a medical condition associated with a wide range of psychiatric and non psychiatric diseases including: mood disorders, schizophrenia, personality disorders and drug dependence. In our pilot, open-label study, we evaluated the effect of a single dose of sublingual asenapine in bipolar patients affected by withdrawal syndrome induced psychomotor agitation resistant to the treatment with agonist medicines (methadone, gamma hydroxybutyrate and benzodiazepines).

journal of reward deficiency syndrome and addiction science

A Single Dose of Asenapine for the Treatment of Bipolar Patients Affected by Withdrawal Syndrome Induced Psychomotor Agitation: A Pilot, Open-Label Study