Open AccessThe effect of chondroitin sodium sulfate on oxidation-antioxidant balance in the blood serum of carrageenan-induced inflammation in the rat hindpaw
Author(s) -
K. Dvorshchenko,
M. Ashpin,
A. Voeikov,
Oleksandr Korotkyi
Publication year - 2015
Publication title -
bulletin of taras shevchenko national university of kyiv series “psychology”
Language(s) - English
Resource type - Journals
eISSN - 2308-8036
pISSN - 1728-3817
DOI - 10.17721/1728_2748.2015.70.53-55
Subject(s) - chemistry , catalase , superoxide dismutase , carrageenan , lipid peroxidation , antioxidant , diclofenac sodium , hydrogen peroxide , inflammation , pharmacology , biochemistry , endocrinology , medicine , chromatography
The significant violation of pro-/antioxidative balance in serum of сarrageenan-induced inflammation in the rat paw was established. It was associated with increased levels of hydrogen peroxide and lipid peroxidation products, as well as with elevated catalase and decreased superoxide dismutase activity. All above mentioned indices was closer to control values in animals treated simultaneously with сarrageenan and drug "Drastop".
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