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AVALIAÇÃO IN VITRO DA CITOTOXICIDADE DO ÓLEO ESSENCIAL DA ERVA INFESTANTE RHAPHIODON ECHINUS (NEES & MART)SCHAUER
Author(s) -
G. T. LIMA,
C. M. R. Sousa,
P. S. PEREIRA,
S. M. A. LIMA,
T. G. SILVA,
A. E. DUARTE
Publication year - 2017
Publication title -
anais do 5º encontro brasileiro para inovação terapêutica
Language(s) - English
Resource type - Conference proceedings
DOI - 10.17648/ebit-2017-85738
Subject(s) - biology
Weeds can be an important source of natural products with promising biological activity. The study of plants that can be used as new therapeutic agents for the treatment of various diseases seems promising. The essential oil was extracted by hydrodistillation in a modified Clevenger type apparatus and analyzed by GC / MS. The cytotoxicity test evaluated NCTC 929 fibroblasts, which were seeded (5x104 cells / well) in 96-well flat bottom microdilution plates with 100 μl of RPMI medium. The results showed that 21 compounds were identified in the essential oil, the main constituent being the γ-

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