EFEITO DO TEMPO DE EXPOSIÇÃO À IRRADIAÇÃO GAMA NA VIABILIDADE DE CÉLULAS-TRONCO MESENQUIMAIS

The mesenchymal stem cells (MSC) are classified as undifferentiated cells that are able to differentiate in specialized cell types, therefore these cells do not present a sensitivity to radiation as predicted by the law of radiosensitivity. In the past few years, researches have shown that these cells are resistant to high doses of radiation, maintaining their DNA intact and their ability to differentiate into osteogenic, chondrogenic and adipogeniclines. However, there are few studies in the literature comparing different times of irradiation of MSC. Thus, the present study aimed to differentiate, by MTT assay, whether there are differences in the cellular viability response when the samples are in vitro irradiated in an acute and protracted manner.