SILVER ATOMS ENCAPSULATED IN G4 PAMAM (POLYAMIDOAMINE) DENDRIMERS AS A MODEL FOR THEIR USE IN NANOMEDICINE FOR PHOTOTHERAPY
Author(s) -
Tamar G. Giorgadze,
Irine Khutsishvili,
Zaza G. Melikishvili,
Vasil G. Bregadze
Publication year - 2020
Publication title -
european chemical bulletin
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.131
H-Index - 5
ISSN - 2063-5346
DOI - 10.17628/ecb.2020.9.22-27
Subject(s) - dendrimer , nanomedicine , chemistry , nanotechnology , materials science , nuclear chemistry , polymer chemistry , nanoparticle
The main goals of the research are to study the drug delivery nanoparticle, G4 PAMAM (polyamidoamine) dendrimer, using spectroscopic and thermodynamic methods and, based on the unique properties of G4 PAMAM dendrimer, create new, stable nano-sized (~5 nm) metalorganic nanocomplexes with silver atoms, which have a strong absorption in visible area and it can be used as a photo thermotherapeutic agent for the treatment of cancer cells.
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