ONE POT SYNTHESIS OF PYRANOPYRAZOLE USING SODIUM LACTATE AS AN EFFICIENT CATALYST
Author(s) -
Jayant P. Sonar,
Sandeep D. Pardeshi,
Shrikant Dokhe,
G. M. Bhavar,
Sunil U. Tekale,
Ashok M. Zine,
Shivaji N. Thore
Publication year - 2019
Publication title -
european chemical bulletin
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.131
H-Index - 5
ISSN - 2063-5346
DOI - 10.17628/ecb.2019.8.207-211
Subject(s) - sodium lactate , chemistry , catalysis , sodium , biochemistry , organic chemistry
An efficient one pot synthesis of pyranopyrazoles has been achieved by the four-component condensation of hydrazine hydrate, ethyl acetoacetate, aldehydes and malononitrile using sodium lactate as a catalyst in aqueous ethanolic medium under reflux condition. The method is simple and green to afford pyranopyrazoles in a short time. It provides a new base catalyst that readily gives product from moderate to excellent yields
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