SIMPLE CHROMIUM CATALYZED OXIDATIVE SYNTHESIS OF QUINAZOLINONES AND BENZOXAZINONES FROM 2-AMINOBENZAMIDE AND ANTHRANILIC ACID WITH ARYLALDEHYDES
Author(s) -
Ashwini V. Izankar,
Aniket P. Sarkate,
P.S. Patil,
Arjun L. Khandare,
Suman Sinha,
Kshipra S. Karnik,
Yogesh W. More,
Dattatraya N. Pansare
Publication year - 2019
Publication title -
european chemical bulletin
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.131
H-Index - 5
ISSN - 2063-5346
DOI - 10.17628/ecb.2019.8.180-187
Subject(s) - anthranilic acid , catalysis , chemistry , oxidative phosphorylation , chromium , simple (philosophy) , combinatorial chemistry , organic chemistry , biochemistry , philosophy , epistemology
An easy and efficient protocol for oxidative synthesis of quinazolinones and benzoxazinones using novel catalyst fromed in- situ from chromium trioxide has been developed. Here chromium trioxide acts as an oxidant and its reduction products catalyze the coupling reaction. Newly developed method demonstrates a new alternative to existing method which is a cost effective approach to synthesize important moieties like quinazolinones and benzoxazinones from easily available starting materials in good to excellent yields.
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