THE REACTION OF ALLOXAN WITH INDOLE AND FURANES. STRUCTURE OF 5-INDOL-3-YL-5-HYDROXYPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE | Zendy

Vasiliy G. Shtamburg | Zendy; A. A. Anishchenko | Zendy; Svitlana V. Shishkina | Zendy; Victor V. Shtamburg | Zendy; А. В. Мазепа | Zendy; Светлана В. Кравченко | Zendy; E.A. Klots | Zendy

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THE REACTION OF ALLOXAN WITH INDOLE AND FURANES. STRUCTURE OF 5-INDOL-3-YL-5-HYDROXYPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE

Author(s) -

Vasiliy G. Shtamburg,

A. A. Anishchenko,

Svitlana V. Shishkina,

Victor V. Shtamburg,

А. В. Мазепа,

Светлана В. Кравченко,

E.A. Klots

Publication year - 2017

Publication title -

european chemical bulletin

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.131

H-Index - 5

ISSN - 2063-5346

DOI - 10.17628/ecb.2017.6.151-154

Subject(s) - indole test , chemistry , alloxan , medicinal chemistry , stereochemistry , biology , endocrinology , diabetes mellitus

The improved syntheses of 5-(indol-3-yl)-5-hydroxypyrimidine-2,4,6(1H,3H,5H)-trione ( 1) , 5-(5-methylfuran-2-yl)-5-hydroxypyrimidine-2,4,6(1H,3H,5H)-trione ( 2) , 5-(5-N,N-dimethylhydrazonylfuran-2-yl)-5-hydroxypyrimidine-2,4,6(1H,3H,5H)-trione ( 3) , 5-(4-N,N-di-methyl-aminophenyl)-5-hydroxypyrimidine-2,4,6(1H,3H,5H)-trione ( 4a) , and 5-(4-N,N-diethylaminophenyl)-5-hydroxypyrimidine-2,4,6 (1H,3H,5H)-trione ( 4b) from alloxane in mild conditions were reported. The structure of 5-(indol-3-yl)-5-hydroxypyrimidine-2,4,6(1H,3H,5H)-trione ( 1) has been determined by XRD study.

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