Open AccessFlexible Stopping Boundaries When Changing Primary Endpoints After Unblinded Interim Analyses
Author(s) -
Liddy M. Chen,
Joseph G. Ibrahim,
Haitao Chu
Publication year - 2014
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/vs02-ke45
Subject(s) - interim , interim analysis , clinical endpoint , primary (astronomy) , early stopping , psychology , medicine , physical medicine and rehabilitation , computer science , clinical trial , history , artificial intelligence , physics , archaeology , astronomy , artificial neural network