Open AccessChimeric Agents Derived from the Functionalized Amino Acid, Lacosamide, and the α-Aminoamide, Safinamide: Evaluation of Their Inhibitory Actions on Voltage-Gated Sodium Channels, and Antiseizure and Antinociception Activities and Comparison with Lacosamide and Safinamide
Author(s) -
Ki Duk Park,
Yang Xiao,
Erik T. Dustrude,
Yuying Wang,
Matthew S. Ripsch,
Fletcher A. White,
Rajesh Khanna,
Harold Kohn
Publication year - 2015
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/snwk-gt85
Subject(s) - lacosamide , inhibitory postsynaptic potential , sodium channel , pharmacology , chemistry , medicine , neuroscience , sodium , psychology , epilepsy , organic chemistry