Open AccessA Highly Conserved Interaction Involving the Middle Residue of the SXN Active-Site Motif Is Crucial for Function of Class B Penicillin-Binding Proteins: Mutational and Computational Analysis of PBP 2 from N. gonorrhoeae
Author(s) -
Joshua Tomberg,
Brenda Temple,
Alena Fedarovich,
Christopher Davies,
Robert A. Nicholas
Publication year - 2012
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/q249-7711
Subject(s) - motif (music) , residue (chemistry) , binding site , chemistry , computational biology , penicillin binding proteins , genetics , penicillin , biology , biochemistry , antibiotics , physics , acoustics