A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease | Zendy

Robert A. Scott | Zendy; Daniel F. Freitag | Zendy; Li Li | Zendy; Audrey Y. Chu | Zendy; Praveen Surendran | Zendy; Robin Young | Zendy; Niels Grarup | Zendy; Alena Stančáková | Zendy; Yuning Chen | Zendy; Tibor V. Varga | Zendy; Hanieh Yaghootkar | Zendy; Jian’an Luan | Zendy; Jing Zhao | Zendy; Sara M. Willems | Zendy; Jennifer Wessel | Zendy; Shuai Wang | Zendy; Nisa M. Maruthur | Zendy; Kyriaki Michailidou | Zendy; Ailith Pirie | Zendy; Sven J. van der Lee | Zendy; Christopher Gillson | Zendy; Ali Amin Al Olama | Zendy; Philippe Amouyel | Zendy; Larraitz Arriola | Zendy; Dominique Arveiler | Zendy; Icíar Avilés-Olmos | Zendy; Beverley Balkau | Zendy; Aurelio Barricarte | Zendy; Inês Barroso | Zendy; Sara Benlloch Garcia | Zendy; Joshua C. Bis | Zendy; Stefan Blankenberg | Zendy; Michael Boehnke | Zendy; Heiner Boeing | Zendy; Eric Boerwinkle | Zendy; Ingrid B. Borecki | Zendy; Jette BorkJensen | Zendy; S. Bowden | Zendy; Carlos Caldas | Zendy; Muriel Caslake | Zendy; L. Adrienne Cupples | Zendy; Carlos Cruchaga | Zendy; Jacek Czajkowski | Zendy; Marcel den Hoed | Zendy; Janet Dunn | Zendy; Helena Earl | Zendy; Georg Ehret | Zendy; Ele Ferrannini | Zendy; Jean Ferrières | Zendy; Thomas Foltynie | Zendy; Ian Ford | Zendy; Nita G. Forouhi | Zendy; Francesco Gianfagna | Zendy; Carlos A. González | Zendy; Sara Grioni | Zendy; Louise Hiller | Zendy; JanHåkan Jansson | Zendy; Marit E. Jørgensen | Zendy; J. Wouter Jukema | Zendy; Rudolf Kaaks | Zendy; Frank Kee | Zendy; Nicola D. Kerrison | Zendy; Timothy J. Key | Zendy; Jukka Kontto | Zendy; Zsofia KoteJarai | Zendy; Aldi T. Kraja | Zendy; Kari Kuulasmaa | Zendy; Johanna Kuusisto | Zendy; Allan Linneberg | Zendy; ChunYu Liu | Zendy; Gaëlle Marenne | Zendy; Karen L. Mohlke | Zendy; Andrew P. Morris | Zendy; Kenneth Muir | Zendy; Martina MüllerNurasyid | Zendy; Patricia B. Munroe | Zendy; Carmen Navarro | Zendy; Sune F. Nielsen | Zendy; Peter M. Nilsson | Zendy; Børge G. Nordestgaard | Zendy; Chris J. Packard | Zendy; Domenico Palli | Zendy; Salvatore Panico | Zendy; Gina M. Peloso | Zendy; Markus Perola | Zendy; Annette Peters | Zendy; Christopher Poole | Zendy; J. Ramón Quirós | Zendy; Olov Rolandsson | Zendy; Carlotta Sacerdote | Zendy; Veikko Salomaa | Zendy; MaríaJosé Sánchez | Zendy; Naveed Sattar | Zendy; Stephen J. Sharp | Zendy; Rebecca Sims | Zendy; Nadia Slimani | Zendy; Jennifer A. Smith | Zendy; Deborah J. Thompson | Zendy; Stella Trompet | Zendy; ­Rosario ­Tumino | Zendy; Daphne L. van der A | Zendy; Yvonne T. van der Schouw | Zendy; Jarmo Virtamo | Zendy; Mark Walker | Zendy; Klaudia Walter | Zendy; Jean Abraham | Zendy; Laufey T. Ámundadóttir | Zendy; Adam S. Butterworth | Zendy; Jennifer L. Aponte | Zendy; Josée Dupuis | Zendy; Douglas F. Easton | Zendy; Rosalind A. Eeles | Zendy; Jeanette Erdmann | Zendy; Paul W. Franks | Zendy; Timothy M. Frayling | Zendy; Torben Hansen | Zendy; Joanna M. M. Howson | Zendy; Torben Jørgensen | Zendy; Jaspal S. Kooner | Zendy; Markku Laakso | Zendy; Mark I. McCarthy | Zendy; James S. Pankow | Zendy; Oluf Pedersen | Zendy; Elio Ríboli | Zendy; Jerome I. Rotter | Zendy; Danish Saleheen | Zendy; Nilesh J. Samani | Zendy; Heribert Schunkert | Zendy; Péter Vollenweider | Zendy; Stephen O’Rahilly | Zendy; Panos Deloukas | Zendy; John Danesh | Zendy; Mark O. Goodarzi | Zendy; Sekar Kathiresan | Zendy; James B. Meigs | Zendy; Margaret G. Ehm | Zendy; Nicholas J. Wareham | Zendy; Dawn Waterworth | Zendy

Open Access

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

Author(s) -

Robert A. Scott,

Daniel F. Freitag,

Li Li,

Audrey Y. Chu,

Praveen Surendran,

Robin Young,

Niels Grarup,

Alena Stančáková,

Yuning Chen,

Tibor V. Varga,

Hanieh Yaghootkar,

Jian’an Luan,

Jing Zhao,

Sara M. Willems,

Jennifer Wessel,

Shuai Wang,

Nisa M. Maruthur,

Kyriaki Michailidou,

Ailith Pirie,

Sven J. van der Lee,

Christopher Gillson,

Ali Amin Al Olama,

Philippe Amouyel,

Larraitz Arriola,

Dominique Arveiler,

Icíar Avilés-Olmos,

Beverley Balkau,

Aurelio Barricarte,

Inês Barroso,

Sara Benlloch Garcia,

Joshua C. Bis,

Stefan Blankenberg,

Michael Boehnke,

Heiner Boeing,

Eric Boerwinkle,

Ingrid B. Borecki,

Jette BorkJensen,

S. Bowden,

Carlos Caldas,

Muriel Caslake,

L. Adrienne Cupples,

Carlos Cruchaga,

Jacek Czajkowski,

Marcel den Hoed,

Janet Dunn,

Helena Earl,

Georg Ehret,

Ele Ferrannini,

Jean Ferrières,

Thomas Foltynie,

Ian Ford,

Nita G. Forouhi,

Francesco Gianfagna,

Carlos A. González,

Sara Grioni,

Louise Hiller,

JanHåkan Jansson,

Marit E. Jørgensen,

J. Wouter Jukema,

Rudolf Kaaks,

Frank Kee,

Nicola D. Kerrison,

Timothy J. Key,

Jukka Kontto,

Zsofia KoteJarai,

Aldi T. Kraja,

Kari Kuulasmaa,

Johanna Kuusisto,

Allan Linneberg,

ChunYu Liu,

Gaëlle Marenne,

Karen L. Mohlke,

Andrew P. Morris,

Kenneth Muir,

Martina MüllerNurasyid,

Patricia B. Munroe,

Carmen Navarro,

Sune F. Nielsen,

Peter M. Nilsson,

Børge G. Nordestgaard,

Chris J. Packard,

Domenico Palli,

Salvatore Panico,

Gina M. Peloso,

Markus Perola,

Annette Peters,

Christopher Poole,

J. Ramón Quirós,

Olov Rolandsson,

Carlotta Sacerdote,

Veikko Salomaa,

MaríaJosé Sánchez,

Naveed Sattar,

Stephen J. Sharp,

Rebecca Sims,

Nadia Slimani,

Jennifer A. Smith,

Deborah J. Thompson,

Stella Trompet,

Rosario Tumino,

Daphne L. van der A,

Yvonne T. van der Schouw,

Jarmo Virtamo,

Mark Walker,

Klaudia Walter,

Jean Abraham,

Laufey T. Ámundadóttir,

Adam S. Butterworth,

Jennifer L. Aponte,

Josée Dupuis,

Douglas F. Easton,

Rosalind A. Eeles,

Jeanette Erdmann,

Paul W. Franks,

Timothy M. Frayling,

Torben Hansen,

Joanna M. M. Howson,

Torben Jørgensen,

Jaspal S. Kooner,

Markku Laakso,

Mark I. McCarthy,

James S. Pankow,

Oluf Pedersen,

Elio Ríboli,

Jerome I. Rotter,

Danish Saleheen,

Nilesh J. Samani,

Heribert Schunkert,

Péter Vollenweider,

Stephen O’Rahilly,

Panos Deloukas,

John Danesh,

Mark O. Goodarzi,

Sekar Kathiresan,

James B. Meigs,

Margaret G. Ehm,

Nicholas J. Wareham,

Dawn Waterworth

Publication year - 2016

Publication title -

carolina digital repository (university of north carolina at chapel hill)

Language(s) - English

DOI - 10.17615/dvr3-xw57

Subject(s) - disease , medicine , computational biology , cardiology , biology

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