Open AccessFBW7 loss promotes chromosomal instability and tumorigenesis via cyclin E1/CDK2–mediated phosphorylation of CENP-A
Author(s) -
M. Takada,
W. Zhang,
A. Suzuki,
T.S. Kuroda,
Zhun Yu,
H. Inuzuka,
D. Gao,
L. Wan,
M. Zhuang,
L. Hu,
B. Zhai,
C.J. Fry,
K. Bloom,
G. Li,
G.H. Karpen,
W. Wei,
Q. Zhang
Publication year - 2017
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/cwvt-ea97
Subject(s) - cancer research , cyclin dependent kinase 2 , cyclin e , genome instability , chromosome instability , microbiology and biotechnology , carcinogenesis , cyclin e1 , cyclin , phosphorylation , biology , cell cycle , dna , genetics , dna damage , protein kinase a , cancer , gene , chromosome