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Human Genome-Wide Association and Mouse Knockout Approaches Identify Platelet Supervillin as an Inhibitor of Thrombus Formation Under Shear Stress
Author(s) -
Leonard C. Edelstein,
Elizabeth J. Luna,
Ian B. Gibson,
Molly S. Bray,
Ying Jin,
Altaf A. Kondkar,
Srikanth Nagalla,
Nacima Hadjout-Rabi,
Tara C. Smith,
Daniel Covarrubias,
Stephen N. Jones,
Firdos Ahmad,
Moritz Stolla,
Xiao–Tang Kong,
Zhiyou Fang,
Wolfgang Bergmeier,
Chad A. Shaw,
Suzanne M. Leal,
Paul F. Bray
Publication year - 2012
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/b6de-6048
Subject(s) - thrombus , shear stress , platelet , knockout mouse , genome wide association study , shear (geology) , biology , genetics , medicine , cardiology , materials science , gene , genotype , immunology , composite material , single nucleotide polymorphism , paleontology