Open AccessThe autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome
Author(s) -
J.J. Yi,
S.R. Paranjape,
M.P. Walker,
R. Choudhury,
J.M. Wolter,
G. Fragola,
M.J. Emanuele,
M.B. Major,
M.J. Zylka
Publication year - 2017
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/9n92-ab10
Subject(s) - ubiquitin ligase , ube3a , dna ligase , ubiquitin , mutant , catenin , wnt signaling pathway , microbiology and biotechnology , chemistry , proteasome , biology , genetics , signal transduction , dna , gene