Open AccessProton-in-Flight Mechanism for the Spontaneous Hydrolysis of N -Methyl O -Phenyl Sulfamate: Implications for the Design of Steroid Sulfatase Inhibitors
Author(s) -
Deborah Edwards,
Richard Wolfenden
Publication year - 2012
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/7ymk-vf09
Subject(s) - steroid sulfatase , steroid , hydrolysis , proton , chemistry , mechanism (biology) , stereochemistry , sulfatase , medicinal chemistry , organic chemistry , biochemistry , enzyme , physics , quantum mechanics , hormone