Open AccessMutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas
Author(s) -
P. Wang,
Q. Dong,
C. Zhang,
Pei Fen Kuan,
Y. Liu,
William R. Jeck,
J. B. Andersen,
W. Jiang,
Gleb L. Savich,
Ting Xu Tan,
J. Todd Auman,
Janelle M. Hoskins,
A Misher,
C. D. Moser,
Scott Yourstone,
J. W. Kim,
K. Cibulskis,
G. Getz,
Heike Hunt,
S. S. Thorgeirsson,
L. R. Roberts,
D. Ye,
K. L. Guan,
Yin Xiong,
L. X. Qin,
Derek Y. Chiang
Publication year - 2013
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/5wp4-fd43
Subject(s) - isocitrate dehydrogenase , idh1 , idh2 , cancer research , dna methylation , pathology , chemistry , medicine , biology , mutation , genetics , gene , enzyme , biochemistry , gene expression