Open AccessVX-809 corrects folding defects in cystic fibrosis transmembrane conductance regulator protein through action on membrane-spanning domain 1
Author(s) -
Hong Yu Ren,
Diane E. Grove,
Oxana De La Rosa,
Scott A. Houck,
Pattarawut Sopha,
Fredrick Van Goor,
Beth J. Hoffman,
Douglas M. Cyr
Publication year - 2013
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/5pzy-8d07
Subject(s) - cystic fibrosis transmembrane conductance regulator , conductance , folding (dsp implementation) , transmembrane protein , regulator , biophysics , cystic fibrosis , domain (mathematical analysis) , action (physics) , transmembrane domain , chemistry , membrane protein , membrane , microbiology and biotechnology , physics , medicine , biology , biochemistry , condensed matter physics , engineering , mathematics , mathematical analysis , receptor , electrical engineering , gene , quantum mechanics