Open AccessLife Beyond Kinases: Structure-Based Discovery of Sorafenib as Nanomolar Antagonist of 5-HT Receptors
Author(s) -
Xingyu Lin,
Xi Ping Huang,
Gang Chen,
Ryan Whaley,
Shiming Peng,
Yanli Wang,
Guoliang Zhang,
Simon X. Wang,
Shaohui Wang,
Bryan L. Roth,
Niu Huang
Publication year - 2012
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/49j7-pm51
Subject(s) - sorafenib , kinase , antagonist , receptor , pharmacology , protein serine threonine kinases , drug discovery , 5 ht receptor , chemistry , medicine , cancer research , serotonin , biochemistry , protein kinase a , hepatocellular carcinoma