Open AccessIn Vivo HIF-Mediated Reductive Carboxylation Is Regulated by Citrate Levels and Sensitizes VHL-Deficient Cells to Glutamine Deprivation
Author(s) -
Paulo A. Gameiro,
Jianguo Yang,
Ana M. Metelo,
Rocío Pérez-Carro,
Rania Baker,
Zongwei Wang,
Alexandra Arreola,
W. Kimryn Rathmell,
Aria F. Olumi,
Pilar López–Larrubia,
Gregory Stephanopoulos,
Othon Iliopoulos
Publication year - 2013
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/1k0b-bj71
Subject(s) - glutamine , in vivo , carboxylation , chemistry , biochemistry , microbiology and biotechnology , biology , genetics , amino acid , catalysis