Pre and post-operative oxidative stress level in cases with ovarian neoplasia | Zendy

Mustafa Bilici | Zendy; Numan Çim | Zendy; Halit Demir | Zendy

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Pre and post-operative oxidative stress level in cases with ovarian neoplasia

Author(s) -

Mustafa Bilici,

Numan Çim,

Halit Demir

Publication year - 2014

Publication title -

medical science and discovery

Language(s) - English

Resource type - Journals

ISSN - 2148-6832

DOI - 10.17546/msd.91746

Subject(s) - oxidative stress , malondialdehyde , medicine , lipid peroxidation , superoxide dismutase , glutathione , antioxidant , catalase , ovarian cancer , endocrinology , cancer , gastroenterology , biochemistry , enzyme , chemistry

Objective: The aim of this study is to analyze the serum antioxidant enzyme activities and oxidative stress levels in patients with ovarian neoplasia. Oxidative stress is considered to play a role in the pathogenesis of many diseases such as cancer, diabetes and heart condition. Antioxidants are involved in the removal of carcinogen lipid soluble radicals produced by lipid peroxidation. Material and Methods: In his study, pre and post-operative serum glutathione (GSH), superoxide dismutase (SOD), serum catalase (CAT) activity, and malondialdehyde (MDA) levels were investigated in the patient with with ovarian neoplasia. Results: The reduced serum glutathione (GSH) activity was observed to decrease in patients with ovarian cancer (p

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