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Acute myeloid leukemia under lenalidomide therapy in a patient with multiple myeloma
Author(s) -
Ali Eser,
Funda Pepedil Tanrıkulu,
Ayşe Tülin Tuğlular
Publication year - 2016
Publication title -
medical science and discovery
Language(s) - English
Resource type - Journals
ISSN - 2148-6832
DOI - 10.17546/msd.84603
Subject(s) - medicine , lenalidomide , multiple myeloma , myeloid leukemia , oncology , thalidomide , dermatology
A 53-year-old patient who had a 7 year history of multiple myeloma was diagnosed with high risk myelodysplastic syndrome while on lenalidomide treatment. Progression to acute myeloid leukemia has occurred during the following 4 months. Like our case, secondary primary malignancies (SPMs) can rarely complicate treatment of multiple myeloma. Although possible association between SPMs in patients receiving lenalidomide can be attributed to previous melphalan use, potential SPM risk with lenalidomide cannot still be ruled out safely

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