The relation of Hereditery Multiple Exostoses and trace elements

Hereditery multiple exostoses (HME) is a rarely autosomal dominant bone tumoral disorder; which is characterized by abnormal ossification especially at long bones. The common symptoms are bone pain, joint movement limitation, malign degeneration, vessel and neuron impression and asymmetry of extremities. Material and Methods:  A 26-year-old male patient (weight 60 kg, height 170 cm) who admitted  to Department of Orthopedics Out-patient Clinic at Cerrahpasa Medical Faculty in July 2013 had been suffering from bone pain and prominences in different parts of his body for 20 years. Other individuals diagnosed with HME were reported in his family history.  The association of a group of trace elements of the patient was analysed at the Department of Biophysics. Conclusion: Until this time there have been no investigation about the association of HME and trace elements. The level of trace elements that play crucial roles in all systems especially bone and renal metabolism should be kept in mind in evaluation of HME patients. For this purpose, familial and environmental trace element level determination would be one of our projects in this study. Key words: Hereditary Multiple Exostoses, osteochondroma, trace element.