Physiology of Spinal Opioids and its relevance for Pain Management Selection
Author(s) -
BM Bujedo
Publication year - 2017
Publication title -
open journal of pain medicine
Language(s) - English
Resource type - Journals
ISSN - 2640-8104
DOI - 10.17352/ojpm.000005
Subject(s) - relevance (law) , pain management , selection (genetic algorithm) , medicine , anesthesia , psychology , physical medicine and rehabilitation , neuroscience , computer science , artificial intelligence , political science , law
To use spinal opioids appropriately, it is necessary to understand the pharmacokinetics and clinical pharmacology of these drugs including which opioids produce selective spinal analgesia and which do not. Briefly, spinal selectivity is highest for hydrophilic opioids and lowest for lipophilic opioids.
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