Open AccessSynthesis and Antimicrobial Evaluation of Some Nitro-Mannich Bases Derived from β-Nitrostyrene
Author(s) -
El-Sayed Mardia Telep
Publication year - 2015
Publication title -
open journal of chemistry
Language(s) - English
Resource type - Journals
ISSN - 2641-3051
DOI - 10.17352/ojc.000003
Subject(s) - antimicrobial , nitro , chemistry , mannich reaction , combinatorial chemistry , reactivity (psychology) , bacteria , organic chemistry , mannich base , gram negative bacteria , biochemistry , catalysis , escherichia coli , biology , medicine , alternative medicine , pathology , genetics , alkyl , gene
The present work focused on exploring the reactivity of β-nitrostyrene towards Mannich reaction with different approaches. The synthesized nitro-Mannich bases were tested as antimicrobial agents that showed high activity against both gram positive and gram negative bacteria.
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