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Extract of feverfew (Tanacetum parthenium) has anti-inflammatory effect with various therapeutic benefits. Alpha-unsaturated gamma-lactones including parthenolide were recognized as part of the major active ingredients but with undesirable allergic reactions.

Identification of antioxidative ingredients from feverfew (Tanacetum parthenium) extract substantially free of parthenolide and other alpha-unsaturated gamma-lactones