Lack of Association between the 4234G/C X-Ray Repair Cross- Complementing 2 ( XRCC2 ) Gene Polymorphism and the Risk of Endometrial Cancer among Polish Population | Zendy

H Romanowicz | Zendy; Magdalena Bryś | Zendy; Ewa Forma | Zendy; Beata Smolarz | Zendy

Open Access

Lack of Association between the 4234G/C X-Ray Repair Cross- Complementing 2 ( XRCC2 ) Gene Polymorphism and the Risk of Endometrial Cancer among Polish Population

Author(s) -

H Romanowicz,

Magdalena Bryś,

Ewa Forma,

Beata Smolarz

Publication year - 2016

Publication title -

journal of gynecological research and obstetrics

Language(s) - English

Resource type - Journals

ISSN - 2581-5288

DOI - 10.17352/jgro.000018

Subject(s) - endometrial cancer , oncology , gene , genetics , medicine , polymorphism (computer science) , biology , cancer , genotype

Objective: One of the major causes of carcinogenesis is loss of genome stability. The double- strand break DNA repair pathway, including X-ray repair cross complementing group 2 ( XRCC2) gene, is implicated in maintenance integrity of genome and therefore could affect endometrial cancer (EC) risk. The purpose of this study was to evaluate the clinical significance of the XRCC2 4234G/C (rs3218384 ) gene single nucleotide polymorphism (SNP) in endometrial cancer patients.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research