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Objective: One of the major causes of carcinogenesis is loss of genome stability. The double- strand break DNA repair pathway, including X-ray repair cross complementing  group 2 ( XRCC2) gene, is implicated in maintenance integrity of genome and therefore could affect endometrial cancer (EC) risk. The purpose of this study was to evaluate the clinical significance of the XRCC2  4234G/C (rs3218384 ) gene single nucleotide polymorphism (SNP) in endometrial cancer patients.

journal of gynecological research and obstetrics

Lack of Association between the 4234G/C X-Ray Repair Cross- Complementing 2 ( XRCC2 ) Gene Polymorphism and the Risk of Endometrial Cancer among Polish Population