Association between LHβR gene variant and infertility | Zendy

Yılmaz Elvan | Zendy; Ozdemir Ayse | Zendy; Onal Mesut | Zendy; Guven Davut | Zendy; Tural Sengul | Zendy; Kocak Idris | Zendy

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Association between LHβR gene variant and infertility

Author(s) -

Yılmaz Elvan,

Ozdemir Ayse,

Onal Mesut,

Guven Davut,

Tural Sengul,

Kocak Idris

Publication year - 2020

Publication title -

international journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

ISSN - 2640-7582

DOI - 10.17352/ijcem.000042

Subject(s) - infertility , luteinizing hormone , in vitro fertilisation , gynecology , female infertility , male infertility , andrology , medicine , human fertilization , biology , hormone , bioinformatics , genetics , endocrinology , pregnancy

Assisted reproductive techniques have been developed for infertility related problems and to offer more treatment options with increased infertility rates. The aim of the study was to investigate the effect of Luteinizing hormone β receptor (LHβR) gene variants on outcome of In Vitro Fertilization (IVF). This study included 69 cases (29 cases with failured of IVF treatment in IVF Center of Ondokuz Mayis University Hospital by comparing with 30 healthy pregnant cases). DNA isolated from all the cases and LHβ gene was analyzed by next generation DNA sequencing method.

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