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Aging can be defined like a progressive and irreversible natural process. Chronic smoking shows the health care absence, 47% male smoking and 12% female smoking. Cigarette contains more than 4000 substances, in which 50 can develop neoplasm and many varied comorbidities like pituitary, thyroid, adrenal and gonadotrophic mismatch. It also affects calcium metabolism, atherosclerosis, type 2 diabetes, skeletal striated musculature dysfunction, muscle mass loss - mainly thighs and arms - and exercise capacity reduction with fatigue complaint and dyspnea at minimal effort.

Therapeutic approach with anabolic steroids in chronic obstructive pulmonary disease: Their role in improving patients’ quality of life