Open AccessLipid nanoparticulate drug delivery system for the treatment of hepatic fibrosis
Author(s) -
Mukherjee Swarupananda,
Dutta Ayon,
Dipanjana Ash
Publication year - 2021
Publication title -
archives of hepatitis research
Language(s) - English
Resource type - Journals
ISSN - 2641-2977
DOI - 10.17352/ahr.000028
Subject(s) - hepatic stellate cell , hepatic fibrosis , drug delivery , liver fibrosis , drug , fibrosis , medicine , pharmacology , nanotechnology , materials science
Irreversible hepatic fibrosis, an excessive production and accumulation of extra cellular matrix by hepatic stellate cells in the liver, becomes a remarkable economic burden in global health care system.Low therapeutic efficacy and undesirable systemic effect of conventional therapies limit their clinical applications to targethepatic stellate cells.
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