Epidemiological and clinical implications in Kidney Transplantation of occult Hepatitis C virus infection
Author(s) -
Teresa Olea,
Inmaculada Castillo,
Carlos Jiménez,
Jesús DíezManglano,
Javier Bartolomé,
MJ Santana,
MO López- Oliva,
Elena González,
Rafael Selgas,
V. Carreño
Publication year - 2019
Publication title -
archives of clinical nephrology
Language(s) - English
Resource type - Journals
ISSN - 2581-3870
DOI - 10.17352/acn.000036
Subject(s) - occult , epidemiology , medicine , kidney transplantation , transplantation , virology , immunology , intensive care medicine , pathology , alternative medicine
Occult Hepatitis C virus (HCV) infection (OCI) is characterized by the presence of HCV-RNA in liver or in peripheral blood mononuclear cells (PBMC) in the absence of serological markers. HCV infection in kidney transplant (KT) recipients is associated with lower patient and graft survival. However, the relationship between KT outcome and OCI is unknown. Our aim was to determine in KT recipients the prevalence, risk factors for OCI, and its prognostic implications. We tested 149 adults KT recipients for the presence of OCI.
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