Autoimmune hepatitis associated Hepatitis C virus infection treated with fi rst generation direct-acting antivirals
Author(s) -
JD Castro Limo,
TA Varasa,
MR Pradillo,
MR Gutierrez,
Gomez Moreno AZ
Publication year - 2019
Publication title -
annals of antivirals and antiretrovirals
Language(s) - English
Resource type - Journals
ISSN - 2692-4625
DOI - 10.17352/aaa.000006
Subject(s) - autoimmune hepatitis , hepatitis c virus , medicine , immunology , pathogenesis , virology , hepatitis c , virus , hepatitis
The hepatitis C virus (HCV) infection has been associated with autoimmune diseases, probably due to the interaction between HCV E2 envelope protein and CD-81 receptor of B lymphocyte and thus, can infl uence the pathogenesis of autoimmune liver diseases [1,2]. Therefore, it seems reasonable to consider the benefi cial effect of direct-acting antivirals (DAAs) for HCV in patients with chronic HCV infection and autoimmune hepatitis (HAI), although evidence is scarce.
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