Open AccessFrom metastasis to the primary tumour: Giant liver metastasis from pancreatic neuroendocrine tumour
Author(s) -
Elena Resina,
José Carlos García-Gil,
Alejandra Rosell Alayza,
Alberto Ezquerra Durán,
Raquel Luengo González,
Leticia González Moreno,
María Caldas,
Cecilio Santander Vaquero
Publication year - 2022
Publication title -
revista española de enfermedades digestivas/revista española de enfermedades digestivas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.331
H-Index - 38
eISSN - 2340-4167
pISSN - 1130-0108
DOI - 10.17235/reed.2022.8758/2022
Subject(s) - medicine , chromogranin a , metastasis , neuroendocrine tumour , nausea , lesion , neuroendocrine tumors , vomiting , biopsy , radiology , pathology , gastroenterology , immunohistochemistry , cancer
We present the case of a 37-years old male, who consulted for an extended history of intermittent nausea and vomiting. Laboratory tests showed moderate elevated bilirubin (1.30 mg/dL) and GGT (106 U/L). An abdominal CT scan performed showed a solid 18-centimetres (cm) mass located in the right liver lobe. A biopsy of the lesion was performed, revealing metastastic cells of a well-differentiated neuroendocrine tumour (NET, G3 (Ki-67: 25%). Further study was performed with MRI, and SPECT-CT, showing a 2-cm lesion in the pancreatic tail suggestive of being the primary NET. Chromogranin A levels were high (114.100 ng/ml). In our case, despite the large size of the liver metastasis a full resection of the tumours was achieved.