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This study was aimed to evaluate the plasma levels of cardiovascular disease biomarkers in naturally infected theileriosis in sheep (Ghezel breed). Theileria species are known to be ruminant blood parasites and involves deleterious effects in the livestock. Blood samples were collected from 30 selected sheep (Ghezel breed), naturally infected with theileriosis (infected group) and same number non-infected ones. Hematological parameters and the plasma concentrations of cardiac troponin I (cTnI), creatine kinase-MB (CK-MB) and homocysteine (Hcy) were determined in all samples. The results revealed that significant increase (P>0.01) in the level of cTnI, CK-MB, and Hcy concentrations in infected sheep compared with non-infected ones. In addition, cardiovascular biomarkers levels increased with aging and parasitemia rate (P<0.01). In conclusion, theileriosis provides evidence of the progression of cardiovascular biomarkers by aging and following elevation of parasitemia rate in Ghezel breed sheep and seems that further attention should be paid on this issue.

Ovine Theileriosis Enhances Cardiovascular Disease Biomarkers in Naturally Infected Sheep (Ghezel breed) in West Azerbaijan, Iran