Antibacterial applications of bacteriophages | Zendy

Mireille Ansaldi | Zendy; Pascale Boulanger | Zendy; Charlotte Brives | Zendy; Laurent Debarbieux | Zendy; Nicolas Dufour | Zendy; Rémy Froissart | Zendy; Sylvain Gandon | Zendy; Claire Le Marrec | Zendy; MarieAgnès Petit | Zendy; Eduardo P. C. Rocha | Zendy; Clara Torres-Barceló | Zendy

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Antibacterial applications of bacteriophages

Author(s) -

Mireille Ansaldi,

Pascale Boulanger,

Charlotte Brives,

Laurent Debarbieux,

Nicolas Dufour,

Rémy Froissart,

Sylvain Gandon,

Claire Le Marrec,

MarieAgnès Petit,

Eduardo P. C. Rocha,

Clara Torres-Barceló

Publication year - 2018

Publication title -

virologie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.121

H-Index - 12

eISSN - 1950-6961

pISSN - 1267-8694

DOI - 10.1684/vir.2019.0805

Subject(s) - microbiology and biotechnology , political science , library science , biology , computer science

In the 1917 article in which Félix d'Hérelle describes his first observations and proposes the name of bacteriophage, he also reports the first use of these viruses to treat bacterial infections, thus giving birth to phage therapy. Soon after antibiotics supplanted bacteriophages. Today, bacteria resistant to multiple antibiotics become a growing public health issue worldwide. This situation has revived research aiming at developing the antibacterial activity of bacteriophages to treat patients as well as diseases in animals and plants. In fact, the areas of applications of bacteriophages as antibacterial are widening as current solutions of chemical nature are questioned. This review summarizes the basic principles of therapeutic applications of bacteriophages and presents recent data in areas where commercial exploitation is occurring or about to emerge.

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