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Focal seizure propagation illustrated by fMRI
Author(s) -
Sonmezturk Hasan H.,
Morgan Victoria,
AbouKhalil Bassel
Publication year - 2011
Publication title -
epileptic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.673
H-Index - 53
eISSN - 1950-6945
pISSN - 1294-9361
DOI - 10.1684/epd.2011.0405
Subject(s) - lateralization of brain function , right hemisphere , electroencephalography , epilepsy , eeg fmri , neuroscience , psychology , neurology , blood oxygen level dependent , audiology , medicine , functional magnetic resonance imaging
We report the pattern of seizure propagation as detected by functional MRI (fMRI) in a 24‐year‐old man with frequent recurrent electrographic seizures. The EEG seizure onset was left occipital with later spread to the left hemisphere and, to a lesser extent, the right hemisphere. The fMRI showed initial increase in blood oxygen level‐dependent (BOLD) signal in the left occipital pole. The increased signal then propagated to the right occipital‐posterotemporal region, and subsequently, the right and left mesial temporal regions. fMRI can be an effective tool to study seizure onset localization and seizure propagation in patients with frequent recurrent seizures.