Toxoplasmic cyst and heart transplant: a case report of serological reactivation in an acute graft rejection context | Zendy

Guillaume Désoubeaux | Zendy; Kévin Perret-Gallix | Zendy; MarieChristine Machet | Zendy; A Sirinelli | Zendy; Éric Bailly | Zendy; Nathalie van Langendonck | Zendy; J. Chandenier | Zendy

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Toxoplasmic cyst and heart transplant: a case report of serological reactivation in an acute graft rejection context

Author(s) -

Guillaume Désoubeaux,

Kévin Perret-Gallix,

MarieChristine Machet,

A Sirinelli,

Éric Bailly,

Nathalie van Langendonck,

J. Chandenier

Publication year - 2012

Publication title -

annales de biologie clinique

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.167

H-Index - 27

eISSN - 1950-6112

pISSN - 0003-3898

DOI - 10.1684/abc.2012.0706

Subject(s) - medicine , gynecology , immunosuppression , context (archaeology) , serology , immunology , antibody , paleontology , biology

We describe the case of a serological reactivation in a Toxoplasma-seropositive subject, following a cardiac transplantation transmitting cysts contained in the myocardial tissue. In a context of acute graft rejection, primary chemoprophylaxis enables to avoid onset of opportunistic toxoplasmosis, emerging with immunodepletion performed by high-dose steroids. Then, we draw up a brief review of the bibliographical literature about pathophysiological mechanisms of toxoplasmic reactivation in heart transplants.

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