Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion | Zendy

Natália Camargo Rodrigues | Zendy; Lívia Assis | Zendy; Kelly Rossetti Fernandes | Zendy; Angela Maria Paiva Magri | Zendy; Daniel Araki Ribeiro | Zendy; Roberta Brunelli | Zendy; Daniela Cristina Carvalho de Abreu | Zendy; Ana Cláudia Muniz Rennó | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion

Author(s) -

Natália Camargo Rodrigues,

Lívia Assis,

Kelly Rossetti Fernandes,

Angela Maria Paiva Magri,

Daniel Araki Ribeiro,

Roberta Brunelli,

Daniela Cristina Carvalho de Abreu,

Ana Cláudia Muniz Rennó

Publication year - 2013

Publication title -

the journal of rehabilitation research and development

Language(s) - English

Resource type - Journals

eISSN - 1938-1352

pISSN - 0748-7711

DOI - 10.1682/jrrd.2012.08.0147

Subject(s) - myod , low level laser therapy , muscle tissue , granulation tissue , skeletal muscle , myogenin , lesion , medicine , regeneration (biology) , laser therapy , wound healing , pathology , anatomy , laser , surgery , myogenesis , biology , physics , optics , microbiology and biotechnology

The aim of this study was to evaluate the effects of 660 nm low-level laser therapy (LLLT) on muscle regeneration after cryolesion in rat tibialis anterior muscle. Sixty-three Wistar rats were divided into a control group, 10 J/cm(2) laser-treated group, and 50 J/cm(2) laser-treated group. Each group formed three subgroups (n = 7 per group), and the animals were sacrificed 7, 14, or 21 d after lesion. Histopathological findings revealed a lower inflammatory process in the laser-treated groups after 7 d. After 14 d, irradiated animals at both fluences showed higher granulation tissue, new muscle fibers, and organized muscle structure. After 21 d, full tissue repair was observed in all groups. Moreover, irradiated animals at both fluences showed smaller necrosis area in the first experimental period evaluated. MyoD immunoexpression was observed in both treated groups 7 d postinjury. Myogenin immunoexpression was detected after 7 and 14 d. The higher fluence increased the number of blood vessels after 14 and 21 d. These results suggest that LLLT, at both fluences, positively affects injured skeletal muscle in rats, accelerating the muscle-regeneration process.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research