Abnormal endocrine tests in a hemodialysis patient.
Author(s) -
Linda A. Hochstetler,
Michael J. Flanigan,
Victoria S. Lim
Publication year - 1994
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.v4101754
Subject(s) - prolactin , medicine , endocrinology , hormone , triiodothyronine , endocrine system , thyrotropin releasing hormone , thyroid , hemodialysis , thyroid stimulating hormone , endocrine gland , thyroid function tests
A home hemodialysis patient with abnormal thyroid function tests and hyperprolactinemia is presented. Abnormal thyroid tests included low total triiodothyronine and low total thyroxine and free thyroxine; the latter was documented by the use of both RIA and direct dialysis equilibrium techniques. Serum thyroid-stimulating hormone was normal, and the thyroid-stimulating hormone response to thyrotropin-releasing hormone stimulation was in the low-normal range. Serum prolactin was elevated to more than twice the normal level, and the prolactin response to thyrotropin-releasing hormone was also blunted. The interpretation, pathogenesis, physiologic significance, and management of these abnormalities are discussed.
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