Open AccessNuclear magnetic resonance spectroscopy in patients with anion-gap acidosis.
Author(s) -
Deepak Malhotra,
Jamie Shapiro,
L.K. Chan
Publication year - 1991
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.v251046
Subject(s) - anion gap , metabolic acidosis , acidosis , spectroscopy , nuclear magnetic resonance spectroscopy , nuclear magnetic resonance , ion , proton magnetic resonance , resonance (particle physics) , chemistry , medicine , physics , atomic physics , organic chemistry , quantum mechanics
Proton nuclear magnetic resonance spectroscopy was performed on blood or urine from five patients with an anion-gap metabolic acidosis. In all of these cases, this methodology allowed the rapid and specific diagnosis of the nature of the metabolic acidosis. In several of these patients, spectroscopic evidence for intoxication with toxic alcohols was obtained. On the basis of these preliminary data, proton nuclear magnetic resonance spectroscopy may be a useful technique in the evaluation of patients with anion-gap acidosis.
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